Second Trimester
Lesson 14
Aromatics
Review of Aromaticity:
Brief recap of aromatic, non-aromatic, and anti-aromatic compounds.
Importance of aromatic stability and delocalized π-electrons.
Diels-Alder Reaction
Introduction to Diels-Alder Reaction:
Explanation of the [4+2] cycloaddition mechanism.
Role of dienes and dienophiles in the reaction.
Mechanistic Steps:
Formation of the cyclic transition state and the product.
Stereochemistry and regioselectivity of the Diels-Alder reaction.
Practical Applications:
Examples of Diels-Alder reactions in organic synthesis and industrial applications.
Benzene Reactions
Electrophilic Aromatic Substitution (EAS):
Detailed review of nitration, sulfonation, halogenation, and Friedel-Crafts alkylation and acylation.
Factors influencing EAS reactions, such as activating/deactivating groups and ortho/para/meta directing effects.
New Benzene Reactions:
Introduction to less common benzene reactions and their mechanisms.
Real-world examples and applications.